Euro Fed Lipid

FEBS

FEBS Workshop 

Microbial Lipids

From
Genomics to Lipidomics

13-15 May 2010, Vienna, Austria
Prater Ferris Wheel
Picture: Wikipedia, Author Guillermo
Co-organised by:
BOKU

Tu Graz

ÖGMBT


Invitation

Microorganisms have been used for a long time as model systems to study biochemical, cell biological and molecular biological processes. The advantage of these systems is obvious: microorganisms are easy to handle and can be used from small scale to the industrial level. This is also the reason why microorganisms are nowadays used in industry for the large scale production of biomolecules and as tools for biotechnology.
 
A big advantage of using microorganisms for biochemical and molecular biological investigations is the fact that these types of cells were the first to be fully sequenced. The genomes of E. coli and yeast were pioneering enterprises in this field which set the stage for future genome analyses. Functional genomics and proteomics were logical consequences of these efforts which allowed scientists obtaining a deeper insight into biochemical and biological process at the cellular level.
 
Among the biomolecules under investigation worldwide lipids have recently gained much attention. It has been shown that lipids are not only components of biological membranes, which protect cells from the exterior space and form the surface of organelles, and storage molecules, which are put on hold for times of requirement, but are also involved in the modulation of enzyme activities and in cell signalling processes. Modern methods of mass spectrometry opened a new field in lipid research which was named lipidomics. In this field the detailed analysis of components allowed to pinpoint cellular effects at the molecular level.
 
Arguments mentioned above clearly demonstrate the importance of lipid research and point out the advantage of microorganisms used for these investigations. Whereas lipid research with other experimental systems has gained access to various research conferences, meetings specifically addressing lipid research of microorganisms have never been organized. For this reason a group of people started an initiative for a Microbial Lipid Conference. The conference to be held in Vienna in May 2010 is meant as the inaugural and kick-off meeting of a series of such conferences which will take place every second year at different locations. The aim of this conference will be to gather experts in the field of microbial lipid research and to discuss fundamental and applied research as equivalent topics.

We are proud that this workshop will be substantially supported by the Federation of European Biochemical Societies (FEBS). Part of this funding is support of Young Scientists through a number of travel and conference grants (see below). Therefore, young researchers are specifically invited to join this workshop and to apply for the available FEBS YTFs.

We kindly invite you to support this initiative by presenting your latest results in Vienna.

Günther Daum

Günther Daum
Chairman of the Scientific Committee


Supporter:

FEBS

BMWF

Martek

Lallemand

AIT

Wienkultur

Febsjournal

Main Topics

1) Lipid metabolism and lipid metabolic enzymes from microorganisms (Neutral storage lipids, sterols, phospholipids, way esters, sphingolipids, exotic lipids)
  • Bacteria
  • Yeast and Fungi
  • Algae
2) Structural properties (biomembranes) and physical properties of microbial lipids

3)  Lipids in pathogenic microorganisms

4) Biotechnological and industrial aspects of microbial lipid production

5) Lipid trafficking

6) Lipid signalling
Hofburg
Hofburg, Vienna, source: Wikipedia, Author Peter Gerstbach

                  
Stephansdom
Stephansdom, Vienna, source Wikipedia, author Andrew Bossi


Scientific Committee

Chairman:  Günther Daum, Graz, Austria

Co-Chairs:

Ivo Feussner, Göttingen, Germany

Bernhard Schuster, Vienna, Austria

Members of the Committee:
 
Christoph Benning, East Lansing, MI, USA
 
Alexander Steinbuechl, Münster, Germany
 
Peter Buetikofer, Bern, Switzerland
 
Paul Roessler, La Jolla, CA, USA
                 

Programme:

Thursday, 13 May 2010
08:00 - 10:00     Registration 
10:00                Welcome 
 
Session: Bacterial Lipids 
10:00 - 10:40     Keynote Lecture: Fatty Acid Synthesis is not only for Lipids
                         J. Cronan, University of Illinois, Urbana, USA 
 
10:40 - 11:00     Transcriptional Regulation of Membrane Lipid Homeostasis in Bacteria

                        C. Rock, Memphis, IL, USA
 
11:00 - 11:30     Coffee Break
 
11:30 - 12:10     Keynote Lecture: Biosynthesis of Neutral Storage Lipids by Members of the Genus Rhodococcus
                        H. Alvarez, Universidad Nacional de la Patagonia San Juan Bosco, Comodoro Rivadavia (Chubut), Argentina
 
12:10 - 12:30     Regulation of Fatty Acid Biosynthesis in Streptomyces coelicolor
                        H. Gramajo, Rosario, Argentina
 
12:30 - 13:30     Lunch
 
 
Session: Structural Properties of Lipids (Biomembranes)
 
13:30 - 14:10     Keynote Lecture: How Lipid Properties determine Protein Structure and Function
                        W. Dowhan, University of Texas, Houston, USA
 
14:10 - 14:30     The Antibacterial Activity of Phospholipase A2 type IIA is Regulated by the Cooperative Lipid Chain Melting Behavior in Staphylococcus aureus.
                        C. Leidy, Bogota, Columbia
 
14:30 - 14:50     Sinorhizobium meliloti Phospholipase C required for Lipid Remodeling during Phosphorus Limitation
                        O. Geiger, Cuernavaca, Mexico
 
14:50 - 15:10     The structure of the Hydrophobic Pocket of the FabF ß-ketoacyl-ACP Synthase determines Substrate Specificity
                        G.E. Schujman, Rosario, Argentina
 
15:10 - 16:20     Postersession + Coffee Break
 
16:20 - 17:00     Keynote Lecture: Nanobiotechnological applications of S-layer Proteins
                        U. Sleytr, University of Natural Resources and Applied Life Sciences, Vienna, Austria
 
17:00 - 17:20     Interactions of Ciprofloxacin with DPPC and DPPG: Fluorescence Anisotropy, ATRFTIR and 31P NMR Spectroscopies and Conformational Analysis
                        H. Bensikaddour, Brussels, Belgium
 
17:20 - 17:40     Roles of the Direct MinE-membrane Interaction in Proper Function of the Min System
                        Y.L. Shih, Taipai, Taiwan  
  
Friday, 14 May 2010
 
Session: Lipids of Yeast and Algae
 
09:00 - 09:40     Keynote Lecture: Sphingolipid metabolism: Lessons from Yeast
                        L. Obeid, Medical University of South Carolina, Charleston, USA
09:00 - 09:20     to be announced

09:20-09:40       Para-aminobenzoic acid is a coenzyme Q biosynthetic precursor in Saccharomyces cerevisiae
                        N.B. Marbois, Los Angeles, USA

 
09:40 - 10:00     The Oily Truth: Oleate Inhibits Steryl Ester Synthesis and causes Liposensitivity in the Yeast
                        M. Connerth, Graz, Austria
 
10:00 - 10:20     Producing Omega-3 Fatty Acids via Fermentation by Genetic Engineering of Yarrowia Lipolytica
                        N.S. Yadav, Wilmington, USA
 
10:20 - 10:40     Squalene in Yeast and its Effect on Lipid Particle Biogenesis
                        M. Spanova, Graz, Austria
 
10:40 - 11:10     Coffee Break
 
11:10 - 11:30     Fatty Acids Synthesis Modulates Alpha Synuclein Toxicity in Yeast
                        Y.Y. Sere, Poitiers, France
 
11:30 - 11:50     Novel Anti-aging Compounds Greatly Extend Yeast Life Span by Targeting a Programmed Necrotic Cell Death Pathway Triggered by the Age-related Buildup of Free Fatty Acids
                        V.I. Titorenko, Montreal, Canada
 
11:50 ? 12:30    Keynote Lecture: Comparing Lipid Trafficking involving Plastids in Plants and Microalgae
                        C.Benning, Michigan State University, East Lansing, USA
 
12:30 - 13:30 Lunch
 
 
Session: Lipids in Pathogenic Microorganisms
 
13:30 - 14:10     Keynote Lecture: New Lessons from an old Eukaryote: Phospholipid Biosynthesis in Trypanosoma brucei
                        P. Bütikofer, University of Bern, Switzerland
 
14:10 - 14:30     Cardiolipin is required for Morphogenesis in Streptomyces
                        P.R. Herron, Glasgow, Great Britain
 
14:30 - 14:50     Myosin Cross-Reactive Antigen of Streptococcus pyogenes M49 Encodes a Fatty Acid Double Bond Hydratase that Plays a Role In Oleic Acid Detoxification and Bacterial Virulence
                        I. Feussner, Göttingen, Germany
 
14:50 - 16:20     Poster Session and Coffee Break
 
16:20 - 17:00     Keynote Lecture: Lipopolysaccharides and lipooligosaccharides of Helicobacter and Campylobacter spp
                        A.P. Moran, National University of Ireland, Galway, Ireland
 
17:30 -19:30      Vienna City tour (guided bus tour)
 
19:30 -              Conference Dinner at Buschenschank Wolff,
                        1190 Vienna, Rathstrasse (on invitation by the Lord Major of Vienna, Michael Häupl)
 
Coaches take you back to the hotel
 
 Saturday, 15 May 2010
 
Session: Biotechnology of Microbial Lipids
 
09:00 - 09:40     Keynote Lecture: Protein Engineering and Application of Enzymes in Lipid Modification
                        U. Bornscheuer, University of Greifswald, Germany
 
09:40 - 10:00     Metabolic Activities in Yarrowia Lipolytica Grown on Glycerol
                        A. Makri, Patras, Greece
 
10:00 - 10:20     Recent Developments in Algae Oil Extraction
                        R.E. Armenta, Dartmouth, Canada
 
10:20 - 10:40     Fatty Acid Alkyl Esters: Perspectives for Production of Alternative Biofuels
                        A. Steinbüchel, Münster, Germany
 
10:40 - 11:10     Coffee Break
 
 
Session: Lipid Signalling
 
11:10 - 11:50     Keynote Lecture: Biosynthesis and Transformation of Fatty Acid Hydroperoxides
                        A. Brash, Vanderbilt University Medical Center, Nashville, USA
 
11:50 - 12:10     A Bisallylic Mini-lipoxygenase from Cyanobacterium  Cyanothece sp. that has an Iron as Cofactor
                        A. Andreou, Göttingen, Germany
 
12:10 - 12:30     Mechanism of Oxidation of bis-allylic Hydroperoxides and Octadecenoic Acids by Manganese Lipoxygenase
                        E.H. Oliw, Uppsala, Sweden
 
12:30 ? 12:50    Allene Oxide Synthase Linked to a Non-lipoxygenase 9R-dioxygenase in the Human Pathogen Aspergillus terreus
                        F. Jernerén, Uppsala, Sweden
 
12:50 ? 13:10    On the Reaction Mechanism of PpoA from  Aspergillus nidulans
                        F. Brodhun, Göttingen, Germany
 
13:10 - 14:00     Lunch
 
14:00 ? 15:30    Poster Session and Coffee Break
 
 
 Session: Lipid Trafficking
 
15:30 - 16:10     Keynote Lecture:  Lipid Traffic via Route One
                         T. Levine, UCL - Institute of Ophthalogy, London, Great Britain
 
16:10 - 16:30     Ecological Relevance of a Virally Encoded Sphingolipid Pathway
                        C.A. Worthy, Plymouth, Great Britain
 
16:30 - 17:10     Keynote Lecture: Structure and Function of Protein and Lipid Complexes Regulating Eukaryotic Phospholipid Transport
                        D. Voelker, National Jewish Medical Research Centre, Denver, USA
 
17:10 - 17:30     Final Discussion and Closing
 



Kaffeehaus
Cafe Hawelka, Vienna, Source: Wikipedia, Author Rüdiger Wölk, Münster

The Venue

The workshop takes place at the University of Natural Resources and Applied Life Sciences, Muthgasse 18, 1190 Vienna, Austria

See the map provided by Google maps

Take Subway U4  to terminal station Heiligenstadt. This station can also be reached  by line S 45. From there it is a 3 min walk.

Map of the Vienna subway system.

Registration

The FEBS requires that all participants (regardless of their status as student, junior or senior scientist) are charged the same registration fee. However, the amount of travel grants depends on the number of junior scientists registered. To distinguish between junior and senior scientists and to calculate the number of travel grants available please register either as junior or senior scientist. A young scientist is by FEBS definition "a graduate student or postdoctoral researcher within five years of obtaining a PhD".

To register for the congress please use the 

ONLINE REGISTRATION 

Make sure to print the invoice as last step of the registration.

or complete the printed registration form (one form per participant) and return it to:
Euro Fed Lipid
P.O. Box 90 04 40
D-60444 Frankfurt/Main, Germany
Phone: +49/69/7917/345, Fax +49/69/7917/564
info@eurofedlipid.org

Registration is valid after receipt at the Euro Fed Lipid headquarters. Conference tickets will be handed out at the registration desk.

Registration Fees

Category Registration Fee
Senior Scientist (Fee is equal for all kinds of participants according to the requirements of FEBS) EUR 500
Junior Scientist (Fee is equal for all kinds of participants according to the requirements of FEBS) EUR 500
Senior Scientist from Vienna (no accommodation) EUR 175
Junior Scientist from Vienna (no accommodation) EUR 175


Registration fees are not subject to value added tax (tax exemption according §4 Nr. 22a UStG).

The All-inclusive registration fee includes:


After registration you will receive an invoice. This invoice is available directly with the online registration procedure (please make sure to print it as last step!)

Paying by Bank Transfer:
Please transfer the total fees (free of bank commission) to:
Euro Fed Lipid
Dresdner Bank AG, Frankfurt/ Main
Account No. 4 900 133 00
BLZ 500 800 00 (Routing Number)
IBAN DE 80 5008 0000 0490 0133 00
SWIFT-BIC: DRES DE FF
Please quote your reference number.

Paying by Credit Card
We accept Visa, MasterCard and AMEX

Cancellation Policy
Cancellations received on or before 1 April 2010 will be refunded minus a 30 Euro processing fee. After that date until 1 May 2010, 50% of the paid registration fee will be refunded. There will be no refund for cancellations after 1 May 2010 or No-Shows. Substitute participants can be named anytime without additional costs.
If the congress is cancelled for whatever reason, paid fees will be refunded. Further recourse is excluded.


Call for Papers

To submit your contribution prepare a one-page abstract according to the abstract model and store it in rich text format (.rtf).
Deadline for poster abstracts is 15 April 2010, the submission of lectures is closed now.

Submit a poster

Submit an invited lecture (closed)

List of papers (Scientific Committee only, password needed)


FEBS Youth Travel Funds (YTF) & Transcontinental Trans YTF Grants

Young Scientists (graduate students and postdoctoral researchers within five years of obtaining a PhD) can apply for a grant from the FEBS Youth Travel Fund (YTF) to defray a portion of their expenses. Moreover, young scientists from non-FEBS countries (North & South America, Africa and Asia) may be eligible to obtain TransYTF grants.
FEBS YTF as well as TransYTF grants cover costs of registration, accomodation and all meals (breakfast, lunch and dinner). Moreover, travel expenses will be paid to each recipient on top of the YTF grant following applicable guidelines. Eligibility criteria to obtain YTF grants or TransYTF grants from non-FEBS countries or other continents are described in detail in the guidelines on the FEBS homepage.
All YTF recipients must be identified and selected by the responsible organizer.
To apply for a grant send your application, including your c.v. and confirmation number of your submitted abstract to
Prof. Dr. Günther Daum
Technische Universität Graz, Institut für Biochemie
Petersgasse 12/2, 8010 Graz, Österreich
Telefon: +43/ 316 873 6462, Fax +43/ 316 873 6952
guenther.daum@tugraz.at
(Absolute) Deadline for applications is 15. February 2010

Vienna

Vienna  is the capital of the Republic of Austria and also one of the nine states of Austria. Vienna is Austria's primary city, with a population of about 1.7 million (2.3 million within the metropolitan area), and is by far the largest city in Austria, as well as its cultural, economic, and political centre. It is the 10th largest city by population in the European Union. Vienna is host to many major international organizations such as the United Nations and OPEC. Vienna lies in the east of Austria and is close to the Czech Republic, Slovakia and Hungary. In 2001, the city centre was designated a UNESCO World Heritage Site and in 2005 an Economist Intelligence Unit study of 127 world cities ranked it first equal with Vancouver for the quality of life.

Fiaker
Picture: Wikipedia, Author Gryffindor

Accommodation

Please indicate your accommodation needs during registration. Accommodation in a three-star hotel in Vienna is included in the registration fee according to the requirements of FEBS.
Please note that your hotel room will be booked after having received your payment.

Useful Links

http://www.wien.info/en?set_language=en

http://www.wien.gv.at/


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