Enzymes in Lipid Modification

March 26 - 28, 2003, Greifswald, Germany

1st Joint Symposium of the Working Group "Biotransformation" of the VAAM and the German Society for Fat Science (DGF)



- To bring together researchers active in the area of enzymatic lipid modification

- To provide a platform to exchange recent achievements in this area covering basic research as well as aspects related to process development / up-scaling using isolated enzymes and whole cell systems

Local Organizer:

Uwe Bornscheuer, Greifswald University, Greifswald, Germany


Christoph Syldatk, Stuttgart University, Stuttgart, Germany
Andreas Schmid, ETH Zürich, Zürich, Switzerland
Oliver May, Degussa AG, Hanau, Germany
Bernhard Hauer, BASF AG, Ludwigshafen, Germany
Günther Daum, Technical University Graz, Graz, Austria
Ivo Feußner, Göttingen University, Göttingen, Germany


Support by Deutsche Bundesstiftung Umwelt (DBU) , Cognis Deutschland GmbH and Degussa AG is gratefully acknowledged.


Untersuchungs-Beratungs-Forschungslaboratorium GmbH, Altlandsberg

VWR International


Wednesday, March 26th

18.00-19.00: Registration

19.00-20.30: Welcome Reception

Thursday, March 27th

8.00-8.30: Registration

8.30-8.35 Opening remarks (U. Bornscheuer)

Hydrolases in Lipid Modification
Morning session, topic: "Lipases"
Chairpersons: G. Daum, P. Adlercreutz

8.35-9.30 Keynote Lecture I J. Pleiss (Stuttgart University, Stuttgart, Germany): "From sequence to function: Understanding specificity and selectivity of lipases"

9.30-10.30 Session I "Lipases - Screening and Design "

9.30-10.00 T. Eggert (KFA Jülich, Jülich, Germany): "Directed evolution of an enantioselective lipase from Bacillus subtilis"

10.00-10.30 F. Carriere (CNRS, Marseille, France): "The C-terminal domain of pancreatic lipase: Functional and structural analogies with C2 lipid- binding domains"

10.30-11.00 Coffee break

11.00-12.30 Session II "Lipases - Applications"

11.00-11.30 G. Hills (Degussa AG, Hanau, Germany): "Industrial scale production of esters using lipases"

11.30-12.00 M. Rüsch gen. Klaas (University of Applied Science, Neubrandenburg, Germany): "Lipase-catalyzed reactive extraction of oilseeds with dialkyl carbonates"

12.00-12.30 "T. K. Yang (Technical University, Lyngby, Denmark) "Application of immobilized Thermomyces lanuginosa lipase in interesterification"

12.30-13.30 Lunch (a range of restaurants can be found close to the conference location)

13.30-15.00 Session III "Lipases - Applications"

13.30-14.00 N. Weber (Federal Research Institute, Münster, Germany): "Phytosteryl esters as cholesterol-reducing food additives by lipase catalysis"

14.00-14.30 D. Pirozzi (Napoli, Italy) "Improvement of the lipase stability in the presence of commercial triglycerides"

14.30-15.00 M. Heinemann (Aachen, Germany): "New insights in lipase-catalyzed esterifications achieved by systematic mathematical modeling

15.00-16.30 Coffee break and poster session

Here is the list of accepted poster presentations

Afternoon session, topic: "Phospholipases"
Chairperson: C. Syldatk

16.30-17.30 Keynote lecture II P. Adlercreutz (Lund University, Lund, Sweden): "Glycerophospholipid conversions catalysed by phospholipases and lipases"

17.30-18.00 M. Egmond (Utrecht University, Utrecht, The Netherlands): Mutagenesis studies of Staphylococcal lipases"

19.00 Bus transfer to the fisher village Wieck (close to Greifswald)

20.00 Buffet Dinner at Restaurant "Utkiek", Wieck (registration required)

Friday, March 28th Whole-Cell Systems / Engineering Aspects

Morning session, topic: "Whole-Cell Systems"
Chair persons: M. Egmond, J. Eck

8.30-9.30 Keynote lecture III J. Ogawa (Kyoto University, Kyoto, Japan): "Lactic acid bacteria as catalysts for conjugated fatty acid production"

9.30-10.00 R. Kalscheuer (Münster University, Münster, Germany): Bacterial Bifunctional Wax Ester Synthases/Acyl-CoA:Diacylglycerol Acyltransferases: a Novel Type of Long-Chain Acyltransferase"

10.00-10.30 G. Daum (Technical University, Graz, Austria): "Triacylglycerol metabolism in the yeast Saccharomyces cerevisiae" 10.30-11.00 Coffee break

11.00-11.30 H. Diehl, Bremen (University): "Competitive incorporation of carotenoids and cholesterol into membranes"

11.30-12.00 C. Syldatk, Stuttgart (Stuttgart University, Stuttgart, Germany): "Investigations on the development of an integrated microbial and enzymatic process (IMEP) for the production of rhamnolipids, L-(+)- rhamnose and ß-hydroxydecanoic acid"

12.00-12.30 H.J. Heipieper (Leipzig, Germany): "The cis - trans isomerase (cti) of unsaturated fatty acids in the bacterium Pseudomonas putida"

12.30-13.30 Lunch

Afternoon session, topic: "Engineering Aspects"
Chair person: J. Ogawa

13.30-14.00 J. Eck (B.R.A.I.N. AG, Zwingenberg, Germany): "Novel enzymes for biocatalytic applications: Enzyme libraries as a blueprint of functional sequence space

new14.00-14.30 J. Lyon, (Diversa Inc., San Diego, USA), "Novel Esterases and Lipases from Biodiversity"

14.30-15.00 U. Schwaneberg, Bremen (International University Bremen, Bremen, Germany): "Laboratory evolution of monooxygenases for industrial applications"

15.00 Closing remarks (U. Bornscheuer)

Download the lecture program as .pdf-document


Please note that the location has changed. The conference will now take place at the Alfried-Krupp-Wissenschaftskolleg, Baderstr. 1, (Entrance is Martin Luther Str. 14!), 17487 Greifswald, Phone: +49 3834-86-190 01 Fax +49 3834-86-190 05

It is located directly at the Greifswald Cathedral.

Here is a map of the surroundings


Conference fees:
until 28. February 2003
after 28. February 2003
Students (members of DGF / Euro Fed Lipid / VAAM)
Free Access
50 Euro 
Students (non-members)
30 Euro
80 Euro 
Academic institutions (members of DGF / Euro Fed Lipid / VAAM)
75 Euro
125 Euro 
Academic institutions (non-members)
100 Euro
150 Euro 
Industry (members of DGF / Euro Fed Lipid/ VAAM)
135 Euro
185 Euro 
Industry (non-members)
160 Euro
210 Euro 

We strongly encourage Non-members to apply for membership by sending the application form.

Conference fees include registration, abstract book and welcome reception. The conference dinner (add 35 Euro) is not included. The conference language is English. For oral presentations, MS PowerPoint / beamer will be the preferred format.


Cancellations received on or before 28. February 2003 will be refunded in full less a 30 Euro processing fee. After that date cancellation charge is 50% of the registration fee. If the congress is cancelled for whatever reason, paid fees will be refunded. Further recourse is excluded.

Room Reservation Form:

alternatively stored as .rtf-File or as .pdf-File or see the Greifswald pages for a list of hotels

Additional Information:

Deutsche Gesellschaft für Fettwissenschaft (DGF) P.O. Box 90 04 40 D- 60444 Frankfurt/ Main Germany Phone: +49 69 7917 533, Fax: +49 69 7917 564 E-Mail: amoneit@dgfett.de

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